CJC-1295, Ipamorelin 10mg
$85.00
CJC-1295 with DAC is a synthetic peptide, analog of the growth hormone-releasing hormone. Though CJC-1295 without DAC has the same effect and stimulates the production and secretion of growth hormone, the addition of Drug Affinity Complex (DAC) is what increases its half-life allowing it to act longer and more potently.
Research in animals also suggests that CJC-1295 with DAC stimulates insulin-like growth factor 1 (IGF-1) and plays a part in a number of physiological processes.
References:
- https://pubmed.ncbi.nlm.nih.gov/16352683/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC2787983/
- https://academic.oup.com/jcem/article-abstract/91/3/799/2843281?redirectedFrom=fulltext
- https://www.researchgate.net/publication/7416716_Prolonged_Stimulation_of_Growth_Hormone_GH_and_Insulin-Like_Growth_Factor_I_Secretion_by_CJC-1295_a_Long-Acting_Analog_of_GH-Releasing_Hormone_in_Healthy_Adults
CJC-1295 also causes the release of GH, but it does so by stimulating the growth hormone releasing hormone receptor. It is also highly selective and has demonstrated positive benefits on bone health, lean body mass, insulin resistance, and muscle growth and development. By combing the two peptides, it may be possible to produce enhanced effects because they stimulate the growth hormone axis via two different mechanisms. Research in animal models using both peptides is likely to show increased benefit without substantially increased side effects. Ipamorelin is likely to raise baseline levels of GH such that CJC-1295 will be able to produce both higher peaks and higher troughs while preserving normal growth hormone pulsatile secretion. The net effect of combing the peptides would be a higher set point for the normal ebb and flow of GH, resulting in improved lean body mass, better muscle development, improved use of insulin, and overall better metabolic function.
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Body protection compound 157, or BPC for short, is a 15 amino acid segment of a specific body protection compound fragment.
Research showed that BPC-157 presents itself with potent cytoprotective properties, protecting cells from gastric mucosal damage. Though this exact mechanism is not yet fully known, researchers believe it has to do with the brain-gut axis which enables the communication between central nervous and endocrine systems.
TB-500 is a synthetic variation of the naturally occurring Thymosin-beta-4, and is built up of 43 amino acids. This peptide plays an important role in polymerization regulation, cell proliferation, migration and differentiation.
Putting these two peptides in a blend together gives a powerful cell protection effect, as well as improved recovery and differentiation on a cellular level.
References:
The BPC157, TB500, KPV, and GHK-Cu Quad Blend is a premium peptide formulation developed for advanced research into healing, regeneration, and anti-aging. This unique combination brings together four peptides that complement each other through distinct biological pathways. BPC157 has been widely studied for its ability to promote tissue repair, improve circulation, and support the stomach and intestinal lining. TB500, the complete Thymosin Beta-4 peptide, plays a vital role in cellular movement and recovery, helping researchers explore mechanisms of wound and muscle regeneration. KPV, a naturally occurring tripeptide, is valued for its anti-inflammatory and antimicrobial activity, helping to regulate immune response and reduce tissue stress. GHK-Cu, a copper-binding peptide, is known to stimulate collagen synthesis and rejuvenate skin and hair cells, promoting overall cellular renewal.
When combined, these four compounds may act synergistically to support studies on recovery and long-term cellular health. The blend is produced in a GMP-certified facility, tested for ≥99% purity, and provided in lyophilized powder form to ensure stability and reliability for laboratory use. Designed strictly for research purposes, this blend offers scientists a powerful tool to study natural healing and regenerative processes.
BPC-157 5mg, TB-500 (Thymosin Beta-4) 5 mg , GHK-Cu 20 mg
(Total Glow Blend)
The BPC-157, TB-500 (Thymosin Beta-4), and GHK-Cu mix is a mix of three different peptides, measured at 5 mg of BPC-157, 5 mg of TB-500, and 20 mg of GHK-Cu, for a total of 30 mg.
Researchers have been interested in BPC-157, a peptide initially isolated from gastric proteins, because of its ability to promote the growth of blood vessels and healing of injured tissue through a range of cellular mechanisms.
TB-500, a naturally occurring fragment of a larger protein, is typically studied for its ability to migrate cells into injured areas. It encourages the formation of new blood vessels, and reduces inflammation, especially in muscle and connective tissue.
The third ingredient, GHK-Cu, is a low molecular weight copper-binding peptide that has been linked in studies to wound healing, collagen synthesis, and even hair growth stimulation.
Together, these three compounds appear to have an effect on the same biological processes, but with a broader effect than any of them would have in isolation.
For example, TB-500 and BPC-157 both cause the growth of new vessels, while GHK-Cu adds another layer of support by activating the growth of the cells that line blood vessels.
On the structural repair side of tissues, TB-500 enables cell migration by promoting actin activity, while GHK-Cu and BPC-157 both influence fibroblasts and collagen to offer support for stronger connective tissue.
A second point of overlap is in reducing inflammation and oxidative stress, and it may be here that researchers are hopeful for these peptides in longer-term recovery studies.
As a result of these synergistic and shared activities, the blend is being investigated for use in everything ranging from musculoskeletal trauma to wound healing and post-surgical recovery.
Ipamorelin is a pentapeptide and a synthetic ghrelin mimetic (acting as a ghrelin agonist) with high growth hormone (GH) releasing potency. Since it mimics ghrelin and binds to its receptors (GH secretagogues receptors) in the brain, it stimulates the release of GH in the pituitary gland; which leads to an increase in plasma GH levels, but also increased levels in GA tract, lungs, heart, liver, kidney and pancreas.
What differentiates Ipamorelin from other growth hormone releasing peptides is that it stimulates GH in a way that’s most similar to that of growth hormone-releasing hormone.
References:
- Raun K, Hansen BS, Johansen NL, Thøgersen H, Madsen K, Ankersen M, Andersen PH. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998 Nov;139(5):552-61. doi: 10.1530/eje.0.1390552. PMID: 9849822.
- Sinha DK, Balasubramanian A, Tatem AJ, Rivera-Mirabal J, Yu J, Kovac J, Pastuszak AW, Lipshultz LI. Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males. Transl Androl Urol. 2020 Mar;9(Suppl 2):S149-S159. doi: 10.21037/tau.2019.11.30. PMID: 32257855; PMCID: PMC7108996.
TB-500 is a synthetic peptide analogue of Thymosin Beta-4 (Tβ4), a naturally occurring protein that plays a vital role in cell structure and tissue repair.
In research models, TB-500 is studied for its ability to regulate actin polymerization, a fundamental process for cell migration, angiogenesis, and wound healing.
Note: This product is intended for research use only and is not for human consumption.
