BPC-157
Price range: $50.00 (USD) through $80.00 (USD)
BPC‑157 (Body Protection Compound‑157) is a stable synthetic pentadecapeptide (15 amino acids) originally derived from a protective peptide found in gastric juice, widely studied for its cytoprotective and regenerative potential.
Preclinical research suggests it may support soft‑tissue repair (tendons/ligaments), modulate inflammation, and influence vascular signaling involved in healing.
Human evidence remains limited, so it is typically positioned as a research compound rather than an approved medicine.
BPC‑157 overview
BPC‑157 is a 15‑amino‑acid peptide investigated for “cytoprotection” (tissue protection) and repair across multiple organ systems, with particular attention to the gastrointestinal tract and musculoskeletal tissues.
It is described as stable in gastric conditions and has been explored in a wide range of animal and experimental models.
Soft‑tissue recovery research
Orthopaedic and sports‑medicine literature frequently discusses BPC‑157 due to preclinical findings suggesting improved healing responses in injured connective tissues.
In tendon‑healing studies (e.g., Achilles tendon models), results have reported enhanced tendon outgrowth and cellular processes involved in repair.
Gut and brain‑gut axis research
Because of its origin and “cytoprotective” framing, BPC‑157 is commonly researched in models of gastrointestinal injury and inflammation.
Review literature also discusses potential relevance to the brain‑gut axis, including effects observed in experimental CNS models.
Safety and status note
Published human data is still limited (including pilot‑type clinical work), so safety, optimal dosing, and long‑term outcomes are not well‑established.
In many markets it is not an approved therapeutic drug and is sold/marketed primarily for research purposes.
References:
-
Sikiric, P., et al. (2016). Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications. Current Neuropharmacology, 14(8), 857-865.
-
Chang, C. H., et al. (2011). The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. Journal of Applied Physiology, 110(3), 774-780.
-
Vukojevic, J., et al. (2020). Pentadecapeptide BPC 157 and the central nervous system. Neural Regeneration Research, 17(3).
-
Gwyer, D., et al. (2019). BPC 157: A peptide for tissue healing. Journal of Orthopaedic Surgery and Research.
Frequently Asked Questions About BPC-157
What is BPC-157?
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide derived from a protective gastric peptide. It consists of 15 amino acids and is extensively researched for tissue repair and healing mechanisms.
What is the purity level of your BPC-157?
Our BPC-157 10mg is USA-manufactured with >99% purity, verified through HPLC and mass spectrometry testing. Third-party lab results and COA available upon request.
How should BPC-157 be stored?
Store lyophilized BPC-157 at -20°C for long-term storage (up to 2 years). Once reconstituted, refrigerate at 2-8°C and use within 30 days for optimal potency.
What is the molecular formula of BPC-157?
BPC-157 has the molecular formula C62H98N16O22 with a molecular weight of 1419.53 g/mol. The sequence is: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val.
How do you reconstitute BPC-157?
Add 2ml of bacteriostatic water to the 10mg vial to achieve a 5mg/ml concentration. Inject the water slowly down the side of the vial and allow to dissolve naturally without shaking (2-3 minutes).
What makes BPC-157 stable in gastric acid?
BPC-157 is highly stable in gastric juice due to its unique pentadecapeptide structure, making it suitable for various research administration routes including oral, intraperitoneal, and topical applications in laboratory settings.
Can BPC-157 be combined with TB-500 in research?
Yes, BPC-157 and TB-500 are commonly combined in research protocols studying tissue repair mechanisms. We offer a pre-mixed BPC-157 + TB-500 blend for simplified research applications.
What research areas commonly utilize BPC-157?
BPC-157 is utilized in tissue repair research, wound healing studies, tendon and ligament research, gastrointestinal protection studies, and vascular system investigations.
Related Products
Body protection compound 157, or BPC for short, is a 15 amino acid segment of a specific body protection compound fragment.
Research showed that BPC-157 presents itself with potent cytoprotective properties, protecting cells from gastric mucosal damage. Though this exact mechanism is not yet fully known, researchers believe it has to do with the brain-gut axis which enables the communication between central nervous and endocrine systems.
TB-500 is a synthetic variation of the naturally occurring Thymosin-beta-4, and is built up of 43 amino acids. This peptide plays an important role in polymerization regulation, cell proliferation, migration and differentiation.
Putting these two peptides in a blend together gives a powerful cell protection effect, as well as improved recovery and differentiation on a cellular level.
References:
The BPC157, TB500, KPV, and GHK-Cu Quad Blend is a premium peptide formulation developed for advanced research into healing, regeneration, and anti-aging. This unique combination brings together four peptides that complement each other through distinct biological pathways. BPC157 has been widely studied for its ability to promote tissue repair, improve circulation, and support the stomach and intestinal lining. TB500, the complete Thymosin Beta-4 peptide, plays a vital role in cellular movement and recovery, helping researchers explore mechanisms of wound and muscle regeneration. KPV, a naturally occurring tripeptide, is valued for its anti-inflammatory and antimicrobial activity, helping to regulate immune response and reduce tissue stress. GHK-Cu, a copper-binding peptide, is known to stimulate collagen synthesis and rejuvenate skin and hair cells, promoting overall cellular renewal.
When combined, these four compounds may act synergistically to support studies on recovery and long-term cellular health. The blend is produced in a GMP-certified facility, tested for ≥99% purity, and provided in lyophilized powder form to ensure stability and reliability for laboratory use. Designed strictly for research purposes, this blend offers scientists a powerful tool to study natural healing and regenerative processes.
BPC-157 5mg, TB-500 (Thymosin Beta-4) 5 mg , GHK-Cu 20 mg
(Total Glow Blend)
The BPC-157, TB-500 (Thymosin Beta-4), and GHK-Cu mix is a mix of three different peptides, measured at 5 mg of BPC-157, 5 mg of TB-500, and 20 mg of GHK-Cu, for a total of 30 mg.
Researchers have been interested in BPC-157, a peptide initially isolated from gastric proteins, because of its ability to promote the growth of blood vessels and healing of injured tissue through a range of cellular mechanisms.
TB-500, a naturally occurring fragment of a larger protein, is typically studied for its ability to migrate cells into injured areas. It encourages the formation of new blood vessels, and reduces inflammation, especially in muscle and connective tissue.
The third ingredient, GHK-Cu, is a low molecular weight copper-binding peptide that has been linked in studies to wound healing, collagen synthesis, and even hair growth stimulation.
Together, these three compounds appear to have an effect on the same biological processes, but with a broader effect than any of them would have in isolation.
For example, TB-500 and BPC-157 both cause the growth of new vessels, while GHK-Cu adds another layer of support by activating the growth of the cells that line blood vessels.
On the structural repair side of tissues, TB-500 enables cell migration by promoting actin activity, while GHK-Cu and BPC-157 both influence fibroblasts and collagen to offer support for stronger connective tissue.
A second point of overlap is in reducing inflammation and oxidative stress, and it may be here that researchers are hopeful for these peptides in longer-term recovery studies.
As a result of these synergistic and shared activities, the blend is being investigated for use in everything ranging from musculoskeletal trauma to wound healing and post-surgical recovery.
CJC-1295 with DAC is a synthetic peptide, analog of the growth hormone-releasing hormone. Though CJC-1295 without DAC has the same effect and stimulates the production and secretion of growth hormone, the addition of Drug Affinity Complex (DAC) is what increases its half-life allowing it to act longer and more potently.
Research in animals also suggests that CJC-1295 with DAC stimulates insulin-like growth factor 1 (IGF-1) and plays a part in a number of physiological processes.
References:
- https://pubmed.ncbi.nlm.nih.gov/16352683/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC2787983/
- https://academic.oup.com/jcem/article-abstract/91/3/799/2843281?redirectedFrom=fulltext
- https://www.researchgate.net/publication/7416716_Prolonged_Stimulation_of_Growth_Hormone_GH_and_Insulin-Like_Growth_Factor_I_Secretion_by_CJC-1295_a_Long-Acting_Analog_of_GH-Releasing_Hormone_in_Healthy_Adults
Ipamorelin is a pentapeptide and a synthetic ghrelin mimetic (acting as a ghrelin agonist) with high growth hormone (GH) releasing potency. Since it mimics ghrelin and binds to its receptors (GH secretagogues receptors) in the brain, it stimulates the release of GH in the pituitary gland; which leads to an increase in plasma GH levels, but also increased levels in GA tract, lungs, heart, liver, kidney and pancreas.
What differentiates Ipamorelin from other growth hormone releasing peptides is that it stimulates GH in a way that’s most similar to that of growth hormone-releasing hormone.
References:
- Raun K, Hansen BS, Johansen NL, Thøgersen H, Madsen K, Ankersen M, Andersen PH. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998 Nov;139(5):552-61. doi: 10.1530/eje.0.1390552. PMID: 9849822.
- Sinha DK, Balasubramanian A, Tatem AJ, Rivera-Mirabal J, Yu J, Kovac J, Pastuszak AW, Lipshultz LI. Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males. Transl Androl Urol. 2020 Mar;9(Suppl 2):S149-S159. doi: 10.21037/tau.2019.11.30. PMID: 32257855; PMCID: PMC7108996.
TB-500 is a synthetic peptide analogue of Thymosin Beta-4 (Tβ4), a naturally occurring protein that plays a vital role in cell structure and tissue repair.
In research models, TB-500 is studied for its ability to regulate actin polymerization, a fundamental process for cell migration, angiogenesis, and wound healing.
Note: This product is intended for research use only and is not for human consumption.
